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Another Nrf2-regulated protein is the stress responsive inducible enzyme heme oxygenase 1 (HO-1), which metabolizes prooxidant heme to the antioxidant pigment biliverdin, ferrous iron and carbon monoxide 8
Diabetes 42, 594603
This is because the harsh environment of the stomachspecifically stomach acid and digestive enzymestends to break down the glutathione molecule before it can reach the small intestine for absorption
Groebner, P
10.1016/S0140-6736(17)32284-5 26
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